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HIV TRANSMISSION AND PREVENTION

HIV TRANSMISSION AND PREVENTION



You can get or transmit HIV only through specific activities, most commonly through sexual behaviors and needle or syringe use.

The FDA has approved more than two dozen antiretroviral drugs to treat HIV infection. 

They're often broken into six groups because they work in different ways. 

Doctors recommend taking a combination or 'cocktail' of at least two of them.

Called antiretroviral therapy, or ART, it can't cure HIV, but the medications can extend lifespans and reduce the risk of transmission
1) Nucleoside/Nucleotide Reverse Transcriptase Inhibitors (NRTIs)

NRTIs force the virus to use faulty versions of building blocks so infected cells can't make more HIV.

2) Non-nucleoside Reverse Transcriptase Inhibitors (NNRTIs)

NNRTIs bind to a specific protein so the virus can't make copies of itself.

3) Protease Inhibitors (PIs)

These drugs block a protein that infected cells need to put together new copies of the virus.

4) Fusion Inhibitors

These drugs help block HIV from getting inside healthy cells in the first place.

5) CCR5 Antagonist

This stops HIV before it gets inside a healthy cell, but in a different way than fusion inhibitors. It blocks a specific kind of 'hook' on the outside of certain cells so the virus can't plug in.

6) Integrase Inhibitors

These stop HIV from making copies of itself by blocking a key protein that allows the virus to put its DNA into the healthy cell's DNA. 

Source: https://www.dailymail.co.uk/health/article-6471779/Is-cure-HIV-pipeline-Dormant-virus-hides-inside-cells-eradicated.html
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